| Item Type | Name |
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Academic Article
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Inhibition of histone deacetylation enhances endotoxin-stimulated transcription but does not reverse endotoxin tolerance.
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Academic Article
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Association of an IL-1A 3'UTR polymorphism with end-stage renal disease and IL-1 alpha expression.
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Academic Article
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Distinct post-receptor alterations generate gene- and signal-selective adaptation and cross-adaptation of TLR4 and TLR2 in human leukocytes.
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Academic Article
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Endotoxin tolerance disrupts chromatin remodeling and NF-kappaB transactivation at the IL-1beta promoter.
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Academic Article
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Alpha2-adrenoceptor stimulation transforms immune responses in neuritis and blocks neuritis-induced pain.
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Academic Article
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Induction of RelB participates in endotoxin tolerance.
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Academic Article
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Assembly of inflammation-related genes for pathway-focused genetic analysis.
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Academic Article
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Toll-like receptor 4-dependent responses to lung injury in a murine model of pulmonary contusion.
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Academic Article
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G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance.
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Academic Article
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RelB sustains IkappaBalpha expression during endotoxin tolerance.
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Academic Article
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Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance.
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Academic Article
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Pulmonary contusion primes systemic innate immunity responses.
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Academic Article
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The NF-kappaB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin tolerance.
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Academic Article
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Curcumin modulates leukocyte and platelet adhesion in murine sepsis.
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Academic Article
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Facultative heterochromatin formation at the IL-1 beta promoter in LPS tolerance and sepsis.
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Academic Article
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Mechanism of neutrophil recruitment to the lung after pulmonary contusion.
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Academic Article
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MicroRNAs regulatory networks in myeloid lineage development and differentiation: regulators of the regulators.
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Academic Article
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Innate immune response to pulmonary contusion: identification of cell type-specific inflammatory responses.
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Academic Article
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Aging does not reduce heat shock protein 70 in the absence of chronic insulin resistance.
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Academic Article
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NAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response.
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Academic Article
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Adoptive transfer of CD34(+) cells during murine sepsis rebalances macrophage lipopolysaccharide responses.
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Academic Article
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The pathogenesis of pulmonary contusion: an open chest model in the rat.
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Academic Article
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Gene silencing in severe systemic inflammation.
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Academic Article
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Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion.
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Academic Article
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Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin.
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Academic Article
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Epigenetic silencing of tumor necrosis factor alpha during endotoxin tolerance.
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Academic Article
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Dynamic and selective nucleosome repositioning during endotoxin tolerance.
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Academic Article
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MicroRNAs distinguish translational from transcriptional silencing during endotoxin tolerance.
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Academic Article
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NAD+-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance.
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Academic Article
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MicroRNA-146a regulates both transcription silencing and translation disruption of TNF-a during TLR4-induced gene reprogramming.
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Academic Article
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Epigenetics, bioenergetics, and microRNA coordinate gene-specific reprogramming during acute systemic inflammation.
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Academic Article
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Adiponectin-deficiency exaggerates sepsis-induced microvascular dysfunction in the mouse brain.
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Academic Article
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Hematopoietic stem-progenitor cells restore immunoreactivity and improve survival in late sepsis.
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Academic Article
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Myeloid-derived suppressor cells evolve during sepsis and can enhance or attenuate the systemic inflammatory response.
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Academic Article
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Fueling the flame: bioenergy couples metabolism and inflammation.
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Concept
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Humans
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Concept
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Blood Glucose
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Concept
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Renilla
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Concept
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Binding Sites
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Concept
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Animals
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Concept
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Blotting, Northern
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Concept
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Aged
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Concept
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African Continental Ancestry Group
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Concept
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Protein Biosynthesis
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Concept
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Mice, Knockout
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Concept
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NF-kappa B p50 Subunit
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Concept
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Blotting, Western
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Concept
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Specific Pathogen-Free Organisms
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Concept
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Mice
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Concept
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Adaptation, Biological
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Concept
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Bone Marrow Cells
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Concept
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Models, Biological
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Concept
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CCAAT-Enhancer-Binding Protein-beta
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Concept
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Adult
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Concept
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Mice, Inbred C57BL
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Concept
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Bronchoalveolar Lavage Fluid
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Concept
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Protein Binding
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Concept
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Hispanic Americans
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Concept
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DNA-Binding Proteins
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Concept
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Transforming Growth Factor beta
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Concept
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Blood-Brain Barrier
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Concept
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NF-kappa B
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Concept
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Aged, 80 and over
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Concept
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Mice, Inbred BALB C
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Concept
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Mice, Obese
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Concept
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Bone Marrow Transplantation
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Concept
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Rats
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Concept
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I-kappa B Proteins
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Concept
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Rats, Wistar
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Concept
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Middle Aged
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Concept
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Rats, Sprague-Dawley
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Concept
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Genetic Vectors
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Concept
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European Continental Ancestry Group
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Concept
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Base Sequence
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Concept
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RNA-Binding Proteins
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Concept
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NFI Transcription Factors
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Concept
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Polysaccharides, Bacterial
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Academic Article
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Mitogen-activated protein kinase phosphatase 1 disrupts proinflammatory protein synthesis in endotoxin-adapted monocytes.
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Academic Article
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MicroRNA-146a and RBM4 form a negative feed-forward loop that disrupts cytokine mRNA translation following TLR4 responses in human THP-1 monocytes.
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Academic Article
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RelB: an outlier in leukocyte biology.
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Academic Article
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Methylomics of gene expression in human monocytes.
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Academic Article
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Complement mediates a primed inflammatory response after traumatic lung injury.
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Academic Article
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MicroRNA 21 (miR-21) and miR-181b couple with NFI-A to generate myeloid-derived suppressor cells and promote immunosuppression in late sepsis.
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Academic Article
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SIRT1 inhibition during the hypoinflammatory phenotype of sepsis enhances immunity and improves outcome.
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Academic Article
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Age-related variations in the methylome associated with gene expression in human monocytes and T cells.
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Academic Article
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Sequential actions of SIRT1-RELB-SIRT3 coordinate nuclear-mitochondrial communication during immunometabolic adaptation to acute inflammation and sepsis.
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Academic Article
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SIRT1 mediates a primed response to immune challenge after traumatic lung injury.
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Academic Article
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Transcriptomic profiles of aging in purified human immune cells.
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Academic Article
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Resveratrol attenuates microvascular inflammation in sepsis via SIRT-1-Induced modulation of adhesion molecules in ob/ob mice.
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Academic Article
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Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease.
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Academic Article
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Processing Body Formation Limits Proinflammatory Cytokine Synthesis in Endotoxin-Tolerant Monocytes and Murine Septic Macrophages.
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Academic Article
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NFI-A disrupts myeloid cell differentiation and maturation in septic mice.
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Academic Article
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GAPDH Binding to TNF-a mRNA Contributes to Posttranscriptional Repression in Monocytes: A Novel Mechanism of Communication between Inflammation and Metabolism.
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Academic Article
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Sirtuins Link Inflammation and Metabolism.
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Academic Article
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Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.
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Academic Article
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Stat3 and C/EBPß synergize to induce miR-21 and miR-181b expression during sepsis.
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Academic Article
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Adiponectin treatment attenuates inflammatory response during early sepsis in obese mice.
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Academic Article
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Long-term outdoor air pollution and DNA methylation in circulating monocytes: results from the Multi-Ethnic Study of Atherosclerosis (MESA).
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Academic Article
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Myeloid Cell-Specific Knockout of NFI-A Improves Sepsis Survival.
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Academic Article
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Correction: Sirtuin-2 Regulates Sepsis Inflammation in ob/ob Mice.
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Grant
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NF-kB and Chromatin Changes in Human Sepsis
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Grant
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EDUCATION IN PATIENT ORIENTED RESEARCH
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Grant
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Epigenetics of Severe Systemic Inflammation
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Grant
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Planning Grant for Institutional Clinical and Translational Science Award
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Grant
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Epigenetics of Severe Systemic Inflammation
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Grant
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FUNCTIONAL AND METABOLIC PROPERTIES OF TOXIC NEUTROPHILS
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Grant
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Function and Metabolic Properties of Toxic Neutrophils
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Grant
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Mitochondrial Biogenesis is Regulated by RelB During Inflammation
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Academic Article
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Frontline Science: Myeloid cell-specific deletion of Cebpb decreases sepsis-induced immunosuppression in mice.
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Academic Article
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Sirtuin 2 Regulates Microvascular Inflammation during Sepsis.
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Academic Article
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The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat.
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Academic Article
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Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis.
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Grant
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Metabolic and Immune Properties of Sepsis
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Academic Article
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Expression of C/EBPß in myeloid progenitors during sepsis promotes immunosuppression.
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Grant
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Redox control over metabolism and mitochondrial bioenergetics directs the course of acute inflammation and sepsis.
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Academic Article
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Sirtuin1 Targeting Reverses Innate and Adaptive Immune Tolerance in Septic Mice.
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Academic Article
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Nfia deletion in myeloid cells blocks expansion of myeloid-derived suppressor cells during sepsis.
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Academic Article
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Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.
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Academic Article
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Antioxidant treatment after injury suppresses second hit immune priming.
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Academic Article
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IL-10 induces an immune repressor pathway in sepsis by promoting S100A9 nuclear localization and MDSC development.
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Academic Article
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Correction for McPeak et al., "Myeloid Cell-Specific Knockout of NFI-A Improves Sepsis Survival".
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Academic Article
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Sirtuins and Immuno-Metabolism of Sepsis.
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Academic Article
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Frontline Science: Monocytes sequentially rewire metabolism and bioenergetics during an acute inflammatory response.
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Academic Article
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SIRT1 Mediates Septic Cardiomyopathy in a Murine Model of Polymicrobial Sepsis.
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Academic Article
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Cysteine thiol oxidation on SIRT2 regulates inflammation in obese mice with sepsis.
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Academic Article
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S100A9 maintains myeloid-derived suppressor cells in chronic sepsis by inducing miR-21 and miR-181b.
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